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Anti-PDCD1/PD-1/CD279 Antibody (Nivolumab) (CAS No 946414-94-4) is a monoclonal antibody widely studied in immunotherapy research originating from humanized antibodies It targets the PD-1 pathway an immune checkpoint that when inhibited can enhance the body s immune response against various cancer cells This antibody functions by blocking the interaction between PD-1 and its ligands PD-L1 and PD-L2 thus restoring the function of T-cells in the tumor microenvironment Common in vitro activity is observed in the nanomolar to low micromolar range It is typically used in cellular assays animal models and drug screening to assess immune response modulation and tumor inhibition Experimental concentrations typically depend on the specific research design
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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
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Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor that inhibits both IL-4 and IL-5 production from Th2 cells and suppresses IgE synthesis. It is an anti-allergic agent with antiasthmatic, anti-inflammatory, and antifibrotic activity.
Orally active Th2 cytokine inhibitor
Inhibits IL-4 and IL-5 production
Suppresses IgE synthesis
Anti-allergic agent
Antiasthmatic activity
Anti-inflammatory activity
Antifibrotic activity
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